You flip over that box or bottle and you look at the ingredient list, only to find you have no idea what half of them are. How is a company supposed to earn trust with the customer if there’s no way to know what a formula consists of? We reviewed and digested hundreds of articles from experts and medical professionals, along with research websites, to offer up what you need to know about diet pill ingredients. The dieter deserves to know exactly what’s in that formula.

Ingredients are the individual parts that make up a weight-loss formula. In order for a company to add them to a supplement they do not need to be clinically proven to work, as long as there are no promises that read as medical statements or advice. In essence, anyone could add water and claim it is an appetite suppressant because drinking makes you feel full. You can’t always take a company on its word – you have to look to science.

Common Ingredients and the Impact of Ingredient Reviews

There are a few favorites on the market like caffeine, green tea, garcinia cambogia, raspberry ketones, hoodia gordonii, green coffee bean extract, synephrine and glucomannan. Some of these have some pretty good clinical support and others just don’t live up to the dieters high expectations.


Caffeine is a stimulant that works to boost metabolism and curb hunger. It can also work as a diuretic to help if you’re retaining fluids. According to the journal Appetite, after two months of treatment, body weight and percentage body fat in obese women were significantly…reduced.

Green Tea

Green tea is another stimulant, that also contains EGCG, that can work to boost metabolism without stimulating the dieter. The Journal of Nutrition states, “These findings suggest that green tea catechin consumption enhances exercise-induced changes in abdominal fat.”

Garcinia Cambogia

This “fad” ingredient doesn’t give the dieter any benefit. According to the Nutrition Journal, “Ten weeks [of] GCE [garcinia cambogia extract] supplementation failed to promote any clinically significant weight-loss and had a minimal effect on % body fat in overweight individuals consuming their habitual diet.”

Hoodia Gordonii

This is another ingredient that dieters should just skip because there’s just no science to back up claims. Regarding hoodia, the Journal of Clinical Pharmacy and Therapeutics concluded, “no published, peer-reviewed randomized controlled trials examining efficacy of Hoodia were found.”


Glucomannan is a water-soluble fiber that can expand in the stomach, leaving the dieter with less room for food when taken before a meal. According to Russell S. Phillips, M.D. (Harvard Medical School), many “products contain sources of soluble fiber, which…could absorb water within the gut, causing increased satiety and lower caloric intake.”

Ingredient Side Effects

At no point in time should the dieter risk overall health and well-being with a diet supplement. Ingredients that can be unsafe for some include synephrine, caffeine, DMAA, ephedra and yohimbe. Side effects have been reported by science and in ingredient reviews.


Side effects associated with synephrine use include increased heart rate, and increased blood pressure. According to the journal Forensic Science and Medicine, “The use of C aurantium for weight loss has little support in the literature.”


This is a clinically proven weight-loss ingredient. According to the National Institutes of Health Office of Dietary Supplements, “Safety concerns not usually reported at doses less than 400 mg/day for adults, significant safety concerns at higher doses.” Some potential side effects include insomnia, nervousness, jitters, and increased heart rate.

Final Thoughts on Ingredients

It’s really simple when it comes to ingredients. Find safe, clinically proven ingredients offered up by a company that is trustworthy. We offer that information in thousands of supplement and ingredient reviews.

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