CholestOff Review – 10 Things You Need to Know

CholestOff Review
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CholestOff by Nature Made is a dietary supplement that claims to “lower blood cholesterol levels.” According to the company behind it, CholestOff “contains active ingredients that block your body’s absorption of cholesterol while improving your cardiovascular health.” CholestOff is neither a remedy for someone with a medical condition nor a weight loss pill – it is merely a preventative supplement.

We wanted our research team to investigate the use of CholestOff in clinical studies to see if it has long-term benefits. So, we looked into the science behind to product to give you the Bottom Line. Read on to learn what we found.

CholestOff can be purchased through their Official Site.

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What is CholestOff?

CholestOff is a nonprescriptive, dietary supplement that claims to “lower the levels of blood cholesterol.” The supplement is also widely prescribed to enhance cardiovascular health and wellbeing.

Nature Made or Pharmavite, LLC is a California-based manufacturer of dietary supplements, multivitamins, and herbal supplements. There is a Better Business Bureau (BBB) page for Pharmavite, LLC but it is not rated yet. Other brands offered by Pharmavite LLC include Equelle, MegaFood, Nurish, and Uqora.

According to Nature Made, CholestOff uses a proprietary blend of plant stanols and sterols called Reducol, a tasteless, odorless ingredient that they state “works as a catalyst that blocks the absorption of cholesterol in the gut.”

Reducol is also a popular ingredient in manufacturing dietary supplements and fatty and nonfat functional foods. Naturally occurring plant sterols and stanols are present in various plants’ leaves, vegetables, and nuts.

Through decades of research, plant sterols and stanols have been useful as a critical ingredient in supplements and drugs.

One serving of CholestOff supplies 0.9g of sterols and stanols in capsule form. Users of CholestOff should consult their physicians as part of the cholesterol management program.

A complete regimen encompasses regular checks of cholesterol levels, a healthy diet, physical exercise, and body weight management.

What does the research have to say about the Reducol component?

  • Journal of Agricultural and Food Chemistry – “Phytostanyl fatty acid esters, which are being added to a variety of foods owing to their cholesterol-lowering properties, are susceptible to thermally induced oxidation reactions.” Such fatty acid esters are found in ingredients like Reducol.
  • National Library of Medicine – You can even add Reducol to plant-sterol enriched milk for positive results on cholesterol levels.
  • Journal of Oleo Science – A direct look into plant sterols in other research again shows a promising impact on cholesterol.

CholestOff Competitors

Cardio Cuts

Customer Service Contact Information

  • Address: 8531 Fallbrook Ave., West Hills, CA 91304
  • Mail: P.O. Box 8531 West Hills, CA 91309-9903
  • Phone: 1-800-276-2878 toll-free Monday – Friday, 8 am to 2 pm (Pacific Time)
  • Contact form:
  • Email: [email protected]

Refund Policy

If you are not completely satisfied with your product, you may request a refund of your payment (less any applicable shipping fees) or a replacement within 30 days of receipt.


What is Cholesterol?

To learn and appreciate the benefits of CholestOff, it is crucial to understand what cholesterol is.

Blood cholesterol is crucial for making hormones and digesting food. However, having too much cholesterol can have effects on your health

According to Nature Made, “CholestOff lowers the level of LDL and Non-LDL cholesterol.” Though Nutrients also note their potential benefits, larger and more comprehensive studies are needed to confirm these findings.

The National Institutes of Health (NIH) advises people who want to manage their cholesterol levels to decrease their dietary intake of saturated fats, trans fat, and cholesterol.

Sterols Vs. Stanols

Sterols and stanols sound an awful lot alike; there are similarities and differences. On a molecular level, both look similar to cholesterol. You can find both in foods, but some companies understand sterols and stanols benefit health, according to the Journal of AOAC International.


CholestOff Ingredients

The active ingredients in CholestOff, are sourced from natural plants such as the pine tree.

The foods with high concentrations of fortified stanols and sterols include granola bars, yogurt, margarine, and orange juice.

Regarding this dietary supplement, four caplets of CholestOff can deliver up to 1.8g of sterols and stanols.

According to the instructions, CholestOff contains no artificial flavors, gluten, preservatives, or yeast. Besides plant sterols and stanols, other ingredients include:

  • Plant Sterols/ Stanols (Pine Tree)
  • Cellulose Gel
  • Polyethylene Glycol
  • Calcium Carbonate
  • Triethyl Citrate
  • Polysorbate 80
  • Tribasic Calcium Phosphate
  • Silicon Dioxide
  • Hydroxypropyl Methylcellulose
  • Croscarmellose Sodium
  • Magnesium Stearate

Hydroxypropyl Methylcellulose is a coating agent many pharmaceutical companies use. While Croscarmellose sodium and Polysorbate 80 works as an emulsifier.

Magnesium stearate is a standard white substance used in the manufacture of some diet pills.

Silicon dioxide helps absorb moisture and is considered an anticaking agent.

Polythene glycol is a popular polyether compound in several medications, while Triethyl citrate is a colorless and odorless liquid that helps stabilize foams. The ingredient is also used by pharmaceutical companies for coating purposes.

Supplements such as CholestOff should not be taken to treat health issues. For this reason, patients are advised to consult the doctor before taking any dietary supplements.

Does CholestOff Work?

Does CholestOff Work?

Some research supports the effectiveness of CholestOff in its claims of reducing blood cholesterol levels. According to the International Journal of Food Sciences and Nutrition, supplementation with a dietary supplement containing plant sterols/stanols reduced the total cholesterol by 2.8%, LDL cholesterol by 4.9%, and non-HDL cholesterol 3.6%.

Most of the reviews concerning CholestOff on sites like are positive.

Sterols are widely available in natural foods such as grains, vegetables, and fruits.

Side Effects

CholestOff Side Effects

There’s no mention of side effects from CholestOff. However, taking CholestOff products are not recommended for children, pregnant or lactating mothers. Restrictions also apply to people with certain medical conditions and those allergic to pine trees and constituent products.


CholestOff Directions

The recommended serving of CholestOff for high cholesterol and other natural support is two capsules, two times a day, which equals a 1,800 mg dosage. The CholestOff Original contains 60 to 120 caplets, depending on the container size.

The supplement is best before meals; Nature Made recommends taking between 15 to 30 minutes before mealtime.

To better swallow the pills, you can drink water before and during consumption.

Where To Buy

Where to Buy CholestOff?

CholestOff Complete Softgels is available on the official website, the 120 softgels bottle cost $42.69.

There is also a location finder on the official website if you would like to purchase the supplement at a store near you.

CholestOff prices range heavily based on where you buy it. For example, a 120 softgels count bottle costs about $38.86 on iHerb.

What Users Are Saying

What Users Are Saying

“This product dropped my cholesterol by 10 points in about a month. Probably would have been lower if I didn’t eat ice cream every other day.”

“I tried it for 2 months and my LDL level actually went up. And I diet and exercise. Just doesn’t work.”

“I had high hopes for this product to lower my genetic cholesterol but it really upset my stomach. (I’ve had this problem with other meds too.) I took only 2 pills per day for about 10 days and the heartburn and indigestion got progressively worse. I did read that this happens in a few cases.”

Bottom Line

The Bottom Line on CholestOff

While many supplements marketed for their ability to lower levels of cholesterol show promise, a few others are neither strong nor effective in lowering the levels of cholesterol.

The results obtained from people using CholestOff can vary, depending on whether the individual has a history of heart conditions, preexistence medical condition, nursing or pregnant.

Before taking CholestOff for weight loss, it is important to understand that there are diet pills, supplements and support programs on the market that are more effective for weight loss.

If you’re looking to improve overall health and increase weight-loss, we suggest going with a program that provides more bang for your buck and scientific evidence that proves it works.

Among the best products we’ve seen this year is one called Noom. The clinically-tested program works to help you lose weight and keep it off. It’s likely the unique approach to weight loss that makes the program successful. You get personalized meal plans, human coaching and much more that you don’t find in other apps.

Also, the makers of Noom are offering customers a free trial offer, which is a sign of confidence in their product.

Learn More About Noom »

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What is CholestOff?


CholestOff is a dietary supplement manufactured by Nature Made that claims to lower blood cholesterol levels and enhance cardiovascular health. It uses a proprietary blend of plant stanols and sterols called Reducol that works as a catalyst to block the absorption of cholesterol in the gut.

Are there any side effects associated with CholestOff?


Some users may experience digestive issues such as constipation, gas, or bloating. However, these side effects are typically mild and go away on their own.

What are the ingredients in CholestOff?


CholestOff ingredients are Plant Sterols/Stanols (Pine Tree), Calcium Carbonate, Tribasic Calcium Phosphate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Silicon Dioxide, Magnesium Stearate, Color Added, Polyethylene Glycol, Triethyl Citrate, Polysorbate 80, and Sodium Citrate.

What is the active ingredient in CholestOff?


CholestOff is a cholesterol-lowering supplement that contains the active ingredient, plant sterols. Plant sterols are natural compounds found in fruits, vegetables and grains like soybeans and wheat. They block the absorption of dietary cholesterol and help balance levels in your bloodstream. CholestOff also includes omega-3 fatty acids, niacin and policosanol which provide additional health benefits.

Does CholestOff work?


There are no ingredients in CholestOff that work to increase weight-loss.

Where can I buy CholestOff?


CholestOff can be purchased using their Official Site.

How much does CholestOff cost?


For a one-time purchase, you can buy it for about $13.00.

What is the recommended dosage for CholestOff?


According to the instructions, users should take two caplets twice daily with water at meals.

Can I take CholestOff if I have a health condition?


You should ask your physician if you have health problems, are under the age of 18, pregnant, nursing, or are taking prescriptions.

What company is behind CholestOff?


Nature Made is the company behind CholestOff.

Does CholestOff contain yeast?


No, CholestOff doesn’t contain yeast, starch, preservatives, synthetic dyes, or gluten.

Do you know of any special deals or discounts on CholestOff?


There are deals and discounts, if you subscribe to get CholestOff once every one to six months; you can save between 5% and 15%.

If you’re looking to lose weight, you may want to look at Dietsupplement Burn’s special trial offer. Users are going crazy over the deal because it’s only the cost of shipping and handling. Click here to check it out!

What is Cholestoff used for?


A dietary formula containing the proprietary phytosterol blends Reducol™ and Pantesin, Nature Made CholestOff® Complete works to lower LDL cholesterol. The plant sterols and stanols inhibit the absorption of cholesterol consumed through the diet.

What is Reducol?


Reducol is a proprietary blend of plant stanols and sterols used in CholestOff to block the absorption of cholesterol in the gut. It is tasteless and odorless and is a popular ingredient in manufacturing dietary supplements and functional foods.

What are sterols and stanols?


Sterols and stanols are naturally occurring plant compounds present in various plants’ leaves, vegetables, and nuts. Through decades of research, they have been found to be useful as a critical ingredient in supplements and drugs

What are the benefits of CholestOff?


CholestOff claims to lower blood cholesterol levels, improve cardiovascular health, and enhance overall wellbeing. It contains active ingredients that block the body’s absorption of cholesterol while improving cardiovascular health.

How much sterols and stanols does one serving of CholestOff contain?


One serving of CholestOff supplies 0.9g of sterols and stanols in capsule form.

Is CholestOff gluten-free?


Yes, CholestOff does not contain gluten, artificial flavors, preservatives, or yeast.

Can CholestOff be used to treat medical conditions?


No, CholestOff is not a remedy for someone with a medical condition. It is merely a preventative supplement.

What is Nature Made?


Nature Made is a subsidiary of Pharmavite LLC, a California-based manufacturer of dietary supplements, multivitamins, and herbal supplements.

What is the refund policy for CholestOff?


Customers who are not completely satisfied with their CholestOff purchase may request a refund of their payment (less any applicable shipping fees) or a replacement within 30 days of receipt.

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