AXIO Review – 12 Things You Need to Know

AXIO Review 

											- 12 Things You Need to Know
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AXIO claims to be a “new approach to energy” that unlocks your brain’s potential. We looked into the powder’s ingredients, potential side effects, and relevant scientific studies to see if that was true. We also went through tons of user reviews. In the end, we gathered all the most important pieces of information to give you the bottom line on this new energy supplement.

AXIO can be purchased through their Official Site.

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What is AXIO?

AXIO is a supplement from LifeVantage that claims to boost energy without the crash that comes with too much sugar or caffeine. Designed and produced with science-based research, AXIO is a dissolvable powder that claims to contain all-natural ingredients.

The supplement comes in both regular and decaf. AXIO Regular comes in four flavors, Green Grape, Dragon Fruit, Sour Cherry, Strawberry Splash, while AXIO Decaf comes in two, Red Raspberry and Purple Grape – and here is what some of the research has to say about these product’s ingredients:

AXIO Competitors

8 Greens

AXIO Directions

Like most dissolvable powders, the consumer should mix AXIO with 12-16 ounces of water, shake or stir well, and then drink. According to LifeVantage’s website, AXIO can be taken any time of the day, or “whenever you need a reliable boost in energy.”

The product description does not provide a recommended number of servings to take a day, nor does it have a maximum safe dosage. However, a side note on AXIO’s information page states that more than one AXIO packet may be needed to achieve the product’s intended effects.


AXIO Ingredients

AXIO ingredients include:

  • B Vitamins (B3, B6, and B12)
  • Magnesium
  • Green Tea Extract
  • Pine Bark Extract
  • L-Theanine
  • Quercetin Dihydrate
  • DMAE Bitartrate

All of these ingredients are supposed to boost your energy without the unwanted side effects.


AXIO Benefits

Many of the potential AXIO benefits are related to its ingredients.

Vitamin B3

Vitamin B3, also known as niacin, is a nutrient they claim boosts brain functionality.

Niacin can be helpful for those with cholesterol issues and can be found in a variety of standard foods.

Vitamin B6

Vitamin B6 is a vitamin that occurs naturally in food, says NIH-ODS. Researchers claim B6 is essential to the body’s ability to produce neurotransmitters, the National Institutes of Health reports.

It is speculated that the vitamin may improve cognitive function, mood, and memory, according to a study review published in the Cochrane Database of Systematic Reviews.

Vitamin B12

Vitamin B12 is a powerhouse vitamin capable of creating and protecting DNA and red blood cells, states the Central European Journal of Immunology.

Vitamin B12 is not naturally produced in the human body and is incapable of being stored for a prolonged period.


Magnesium is a crucial element of the human body.

It regulates blood pressure, promotes skeletal strength, and improves heart health, according to the journal Nutrients.


Caffeine Anhydrous is a stimulant that increases alertness.

Apparently, it does this by tricking your brain into stopping the production of adenosine, the chemical that causes you to feel tired, Life Sciences reports.

AXIO Proprietary Blend

AXIO contains a proprietary blend of DMAE, green tea extract, New Zealand pine bark, l-theanine, and quercetin.


Per the American Journal of Clinical Dermatology, DMAE is a molecule widely known as an anti-aging chemical.

It is suspected DMAE fights the cognitive impairment that comes with age by assisting in producing neurotransmitters, PubChem reports.

Green Tea Extract

Green Tea Extract comes from the Camellia sinensis plant and is known widely as a favorite superfood in healthy lifestyle circles. Evidence indicates it is useful in correcting blood pressure and treating high cholesterol.

It is a natural source of caffeine, so some use it to improve mental alertness and cognitive function.

New Zealand Pine Bark

New Zealand Pine Bark from the plant Pinus Radiata, is a traditional medicine that has been used in the rural parts of New Zealand for hundreds of years.

Additionally, it has anti-inflammatory effects and assists with cognitive function.


Suntheanine, or l-theanine, is an amino acid said to encourage relaxation and concentration.

Clinical trials have indicated its ability to lower stress and tension in consumers.


Quercetin is a flavonoid with antioxidant and anti-inflammatory effects. It is most effective against prostate inflammation and pain.

It can also suppress the enzyme that releases cortisol—lovingly known as the “fight or flight” hormone—protecting the brain from high-stress levels, partly based on research in Toxicology and Applied Pharmacology.

AXIO Nutritional Information

AXIO has no artificial colors, flavors, sweeteners, sugars, GMOs, or gluten. It is also vegan. All ingredients used in AXIO have been approved by the Banned Substances Control Group.

The caffeine amounts found in AXIO serving is 100mg, which is less caffeine per ounce than a cup of coffee.

AXIO’s other ingredients include maltodextrin, natural flavors, citric acid, stevia extract, natural colors, gum acacia, guar gum, xanthan gum, malic acid, and ascorbic acid. Most of these ingredients appear to be added to enhance AXIO’s taste and appearance instead of contributing to its ability to improve cognitive function.

AXIO and Nrf2

AXIO’s product description is a little less clear on its relationship with Nrf2, as it claims to possess “Nrf2 ingredients.” Nrf2 is a powerful protein that lies dormant within our body’s cells until released by an Nrf2 activator.

Once activated, Nrf2 can fight against our bodies’ natural destruction by producing illness-fighting enzymes such as Glutathione, Catalase, and Superoxide Dismutase.

These enzymes play a large role in protecting our body from illness and cell mutation as we get older. LifeVantage sells other products that claim to be Nrf2 activators.


AXIO Product Warnings

LifeVantage does not express any concern about risks or side effects associated with their product.

However, there is a definite warning under their product’s label info that claims AXIO is not recommended for minors, pregnant or nursing mothers, or those with an intolerance or insensitivity to caffeine.

They also state that the Food and Drug Administration’s (FDA) recommended intake of caffeine should not exceed 400mg per day.

LifeVantage’s website states that to receive “all the benefits” of the product, the consumer may need to drink more than one serving of AXIO a day.

Paying mind to the FDA’s caffeine intake recommendation, a consumer should probably take no more than three servings of AXIO per day. LifeVantage does not explicitly state this or provide any other maximum safe dose on its product or website.

Does It Work?

Does AXIO Work?

LifeVantage is confident they have science on their side. AXIO’s product page is full of words like “smart blend of ingredients” and “Nrf2 engineered energy,” but they don’t actually explain the science behind their claims.

Although the ingredients found in AXIO can be found in various other supplements, most scholarly sources conclude that more research is needed. Most of the “science” behind AXIO is based on speculation and correlations that may or may not indicate cause and effect.

The LifeVantage website explicitly states that the FDA has evaluated none of the claims made about AXIO’s benefits. All the health benefits of AXIO are “based on historical/documented use” of the product.

The only claim about the product that is supported by scientific research is the effects of caffeine. Caffeine increases alertness and can temporarily improve focus. Nothing can be said about this in regards to AXIO Decaf, as it supposedly contains no caffeine.

Many of the ingredients, such as Vitamin B6, Vitamin B12, Magnesium, and DMAE, are thought to improve cognitive function, help overall mental health and mood.

However, evidence to definitively support or deny the claims made by LifeVantage about their product isn’t readily found.

Potential Side Effects of AXIO

LifeVantage does not explicitly warn its consumers about any adverse or unintended side effects on AXIO’s product page. Part of AXIO’s appeal seems to be that, unlike its competitors, it has no unwanted side effects.

Combined with the newness of the product and the lack of reviews, it is difficult to confirm or deny if anyone has experienced side effects resulting from taking AXIO.

However, there are a few things about AXIO’s ingredients worth mentioning for the conscientious consumer.

AXIO contains 24mg of vitamin B3, which is 150% of the suggested daily value. Deficiencies in niacin are extremely rare, and unlike other vitamins, the possibility of consuming too much niacin is a real concern.

Too much Niacin can cause stomach irritation, nausea, liver damage, impaired blood sugar control, blurred vision, and gout. Nutritionists recommend consulting your doctor before taking Niacin as a supplement.

Side effects of DMAE may include:

  • Drowsiness
  • Elevated blood pressure
  • Confusion
  • Headaches
  • Weight Loss
  • Trouble sleeping

AXIO Price

Since LifeVantage is an MLM company, individual consumers are unable to purchase AXIO directly from the website. However, the product can be found through LifeVantage’s distributors and sites like eBay and Bonanza.

AXIO’s exact price is a little unclear, with distributors selling it for close to $30, while other sources claim it is $50-$60 per shipment.

Each shipment contains 30 servings or package, making AXIO $1.67-$2.00 per serving.

Other products:

  • PhysIQ™ Whey Protein
  • PhysIQ™ Fat Burn
  • ProBio
  • IC Bright™

Axio Lawsuits

As of 2018, Lifevantage was part of a class-action lawsuit currently being presided over in the state of Utah. The suit claims the MLM business is nothing more than a pyramid scheme, according to TruthinAdvertising. No updates have been added since the initial reporting.

What Users Are Saying

What Users Are Saying

“This drink tastes great and gives me so much energy when I take it regularly. Better than coffee and without the jitters. Makes me feel more alive.”

“I had an allergic reaction to this product. I’m not sure what caused it. I have no allergies ever reported in the 3 decades plus of life I’ve had. My wife tried it and she was fine.”

“This stuff is great if you have a child that struggles in school with focusing and paying attention. My 12 year old takes this once a day at school. She mixes it in her water and loves it. She can tell a difference when she takes it and knows it definitely helps her. It does not last all day so she will take it at a time when she feels is best for her. She loves taking it when she has a test and the flavor is good too. I refuse to put my kid on meds and this definitely fills the gap and provides what she needs to be successful in school.”

Bottom Line

The Bottom Line on AXIO

So, can AXIO increase your energy like no other? The jury is still out. However, we have four concerns about this product:

  1. LifeVantage is vague and nonspecific about dosing information.
  2. Multi-leveling marketing companies can be a hassle to deal with as an individual consumer.
  3. It’s such a new product, and there are few testimonials we trust available right now.
  4. There is little scientific evidence to support the claims made by LifeVantage.

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What is AXIO?


AXIO is a dissolvable powder supplement from LifeVantage that claims to boost energy without the crash that comes with too much sugar or caffeine. It comes in both regular and decaf versions and contains all-natural ingredients.

Does AXIO contain caffeine?


Regular AXIO contains caffeine, but AXIO Decaf supposedly contains no caffeine.

What are the benefits of Axio?


Axio offers a variety of health benefits for those looking to optimize their nutrition and overall wellness. Axio contains a blend of essential vitamins, minerals, and plant compounds that work synergistically to support your body’s natural defenses, control oxidative damage, and boost energy levels. It is also designed to provide maximum nutrient absorption for optimal utilization by the body. Axio can help you maintain overall balance as well as support your heart, brain, mood, skin health, immune system and metabolism.

Are the claims made by LifeVantage about AXIO supported by scientific research?


Most of the “science” behind AXIO is based on speculation and correlations that may or may not indicate cause and effect. The only claim about the product that is supported by scientific research is the effects of caffeine.

What are the ingredients in Axio?


The ingredients in Axio are green tea extract, DMAE, quercetin, magnesium, suntheanine, vitamins B6, B3 and B12 and New Zealand tree bark.

Where can I buy AXIO?


AXIO can be purchased using their Official Site.

Does AXIO have any side effects?


LifeVantage does not explicitly warn its consumers about any adverse or unintended side effects on AXIO’s product page. It is difficult to confirm or deny if anyone has experienced side effects resulting from taking AXIO.

Does Axio work?


Considering some scientifically proven ingredients in the formula, Axio should help improve alertness and boost energy. However, not much evidence of scientific studies on the effectiveness of the product for these purposes were available.

What is the price of Axio?


The monthly auto-shipment of Axio Regular and the Axio Decaf containing 30 packs cost $50.99 for each while the retail purchase sells for $60.99 on the official website.

Where can I buy Axio?


Axio is available for sale on the official website, and on Amazon.

How should I take Axio?


Pour a packet of Axio in 12 to 16 ounce of cold water, shake for not less than 30 seconds until well mixed before consuming.

How do I contact Axio customer service?


You can contact Axio customer service for distributor assistance by text or call on 866-460-7241 or via email at [email protected] or call the corporate office contact number on 1 (866) 460-7241.

Can I return Axio?


Yes. You can return and get refunded less handling and shipping charges within 30 days of your order. Only defective or unopened products will be accepted for a refund.

What are the most common complaints with Axio?


Not much of user reviews are available about Axio for common complaints evaluation, though, a few unrelated complaints exist.

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